Carolina Panthers host Detroit Lions at Bank of America Stadium on Monday in Week 4 of the 2026 NFL season. Here’s our preview and best markets.
Sunday Night Football provides us with an intriguing clash between the Carolina Panthers and Detroit Lions, with prime-time regular-season football returning to Carolina for the first time in over a decade.
The Panthers have been at the bottom of the barrel in the NFL for a while, but perhaps, with Bryce Young, they’ve found a guy who could navigate them out of the doldrums.
On the other side of this clash are the Lions, who were once in the same position as the Panthers but managed to claw their way out. They’re now expected to be a team that makes playoff runs year in, year out.
When looking at this game as a whole, there are issues both sides need to fix on their rosters. Most of them have to do with the teams’ defences, which is why I can see this one going over the points total.
Tips
Best: Over 51 Total Points @ $1.92
Anytime Touchdown Scorer: Amon-Ra St. Brown @ $1.85
SGM: Over 51 Total Points, Amon-Ra St. Brown ATS and Bryce Young 250+ Passing Yards
@ $4.61
Carolina Panthers vs Detroit Lions Odds & Popular Betting Markets
Here’s a quick look at the current odds and popular betting markets for the Carolina Panthers vs Detroit Lions matchup.
*odds are correct at the time of publishing and are subject to change
| Team | Odds | |
|---|---|---|
| Detroit Lions (-3.5) | 1.88 | Bet Now |
| Carolina Panthers (3.5) | 1.92 | Bet Now |
NFL odds correct as of 04/10/2026 and subject to change. Event scheduled to start at 05/10/2026 1:20pm NZDT.
NFL odds correct as of 04/10/2026 and subject to change. Event scheduled to start at 05/10/2026 1:20pm NZDT.